Alkis Zopoglou actively begins his pursuit of music from a very early age, playing percussion, and later clarinet. Very soon, he meets the kanun and is performing ever since. For eight years he systematically takes lessons in Istanbul. There, he studies and meets the styles of performance of various important kanun players of Istanbul, such as Ahmet Meter, Halil Karaduman, Goksel Kartal and Goksel Baktagir.
He is a licensee in Byzantine music, and from 1996 to 2003 he has been employed as a substitute professor at the Music School in Drama, teaching kanun.
Till today, he has developed an intense artistic activity. He takes part in several cultural events and in discography, with a significant number of prominent composers and bands of Greece, (Chronis Aidonidis, Nikos Saragoudas, Stamatis Kraounakis, Haig Yazdjian, Nikos Filippidis, Theo Kapilidis, En Chordais, and others). He is also co-operating with many foreign musicians like Theodossi Spassov, Sellahadin Maraqa, Ara Digjian, Kudsi Erguner, Suleiman Erguner, Imane Homsy, Charbel Rouhana, Samir Siblini, Fahrettin Yarkin, Necip Gulses, Hossein Omouni, Kiya and Ziya Tabassian, Ghada Shbeir, Rima Khcheich and others. He has travelled for concerts in many foreign countries (Germany, France, USA, Canada, Australia, Tasmania, Netherlands, Egypt, Italy, Lebanon, Jordan, Turkey, Kazakhstan, Mexico, China, Seoul, UAE, Israel, Bulgaria, Cyprus, Kuwait, Hong Kong, Oman, Romania, Finland, Sweden, United Kingdom, Ukraine and others). He has represented Greece as a musician and has taught Kanun in international Kanun meetings in Egypt, Jordan, Lebanon Cyprus and Romania.
He is a founding member of the musical ensemble Kontrabando and artistic director of mediterranean music festival: mmfestival.ch